GATAD2B anticorps

N° du produit ABIN2461904

L’anticorps Lapin Polyclonal anti-GATAD2B a été validé pour WB et ELISA. Il convient pour détecter GATAD2B dans des échantillons de Humain, Souris, Rat et Chien.

Aperçu rapide pour GATAD2B anticorps (ABIN2461904)

Antigène: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATAD2B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GATAD2B anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GATAD2B.

Information d'application

Indications d'application: GATAD2B antibody can be used for detection of GATAD2B by ELISA at 1:312500. GATAD2B antibody can be used for detection of GATAD2B by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GATAD2B antibody at -20 °C.

Détails sur GATAD2B

Antigène: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Autre désignation: GATAD2B

Sujet: Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta). Both proteins interact with MBD2 and MBD3 functionally and biochemically. Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa. Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern. These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.

Poids moléculaire: 65 kDa

ID gène: 57459

NCBI Accession: NP_065750

UniProt: Q8WXI9